Association between NT-proBNP and the risk of incident heart failure, overall and stratified by status of obesity.

a Person years are calculated from the sub-cohort (n = 1,163) only.b adjusted for sex, stratified for baseline age.c Model 1 further adjusted for educational degree, physical activity, smoking status, alcohol consumption, waist circumference, and prevalent diseases (diabetes, coronary heart disease, hypertension).d Model 2 further adjusted for biomarkers (hsCRP, creatinine, total cholesterol and HDL cholesterol).*p for trend across tertiles was calculated by using tertiles of N-terminal pro brain natriuretic peptide (NT-proBNP) as a categorical variable in the respective Cox proportional hazards regression models.$the p value for nonlinearity was calculated by Wald chisquare test following restricted cubic spline Cox regression analysis.#in the non-stratified models, body mass index (BMI) was also included in the adjustment set.Association between NT-proBNP and the risk of incident heart failure, overall and stratified by status of obesity.