Crystal structure of the L317I mutant of the C-src tyrosine kinase domain complexed with pyrazolopyrimidine 5
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Crystal structure of the L317I mutant of the C-src tyrosine kinase domain complexed with pyrazolopyrimidine 5 Descriptor: 1-{4-[4-amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]phenyl}-3-[3-(trifluoromethyl)phenyl]urea, Proto-oncogene tyrosine-protein kinase Src Authors: Boubeva, R, Pernot, L, Perozzo, R, Scapozza, L. Deposit date: 2011-02-02 Release date: 2012-02-08 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.75 Å) Cite: A single amino-acid dictates the dynamics of the switch between active and inactive C-src conformation To be Published
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2011-02-02
