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Epigenome comparisons reveal linkage between gene expression and developmental remodeling of chromatin domain topology

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NIAID Data Ecosystem2026-05-25 收录
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We describe a new approach to ChIP-seq analysis in which conservation of nucleosome-scale H3K27me3 topology, rather than coverage, is quantified; RNA-seq results are related to the new ChIP-seq approach. Overall design: Examination of histone H3K27me3 modification profiles in human monocytes and dendritic cells, and linkage of histone mark profiles to RNA-seq data

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2018-03-01
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