WDR5 facilitates cholangiocarcinoma metastasis and EMT by promoting HIF-1a accumulation via directly interaction with c-Myc and HDAC2-PHD2 axis
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https://www.ncbi.nlm.nih.gov/sra/SRP258987
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WDR5 was an important co-factor for c-Myc-induced transcriptional activation and malignant progression. We analyzed the differentially expressed genes in scramble and shWDR5 QBC-939 cells. Overall design: QBC-939 cells were stably transfected with scramble shRNA(scr) and WDR5-knockdown shRNA(sh) and subjected to differential gene expression studies by RNA-seq
创建时间：
2021-02-25
