Sindbis virus structural polyprotein -1 PRF deep mutational scan
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https://www.ncbi.nlm.nih.gov/sra/SRP314863
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To probe the sequence constraints of -1PRF, we employed DMS to map the effects of mutations on ribosomal frameshifting within the SINV structural polyprotein. Mutagenic effects were assessed in the context of a reporter that selectively generates a fluorescent protein (mKate) as a result of -1PRF during translation and processing of the SINV structural polyprotein
创建时间:
2021-04-14



