Effect of L-Proline on mouse embryonic stem cells (ESCs)
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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资源简介：
We found that the non-essential amino acid L-proline (L-Pro) acts as a signaling molecule that promotes the conversion of embryonic stem cells (ESCs) into mesenchymal-like, spindle-shaped, highly motile, invasive pluripotent stem cells.This embryonic stem cell-to-mesenchymal-like transition (esMT) is accompanied by a genome-wide remodeling of the H3K9me3 and H3K36me3 histone marks.
提供机构：
Max Planck Institute of Psychiatry
创建时间：
2022-02-20
