Elucidating the regulation of the Yeast Metabolic Cycle through the integration of gene expression and chromatin status

YMC has been characterized in different molecular levels, proving to be a good model to study crosstalk between histone modification and gene regulation. In this study, we used different statistical methodologies to integrate histone modifications and gene expression dataYMC已在多种分子水平上得到特征化表征，被证实为研究组蛋白修饰（histone modification）与基因调控（gene regulation）之间交叉对话（crosstalk）的优良模型。本研究采用多种统计学方法，整合了组蛋白修饰数据与基因表达数据（gene expression data）。