An NMR titration method has been developed to simultaneously measure the difference in acid dissociation constants (ΔpKa) of two or more compounds with high precision and accuracy. The ΔpKa between th
Supplementary Figure 7. NMR titration of unlabeled TPR2A to 15N-labelled psyn129. a. The concentration of psyn129 was kept constant at 100 µM (estimated by Lowry assay), while the concentrations o
Supplementary Figure 7. NMR titration of unlabeled TPR2A to 15N-labelled psyn129. a. The concentration of psyn129 was kept constant at 100 µM (estimated by Lowry assay), while the concentrations of TP
The ability to isolate or enrich specific genomic loci for downstream analyses has transformed ourunderstanding of molecular and cellular biology1. Molecular inversion probes (MIPs) are short single s