Effect of IL-13 and Vitamin D treatment on gene expression and epigenetics in the esophageal epithelial cell line EPC2

We report RNA- and ChIP-sequencing profiling of the esophageal epithelial cell line EPC2 in response to IL-13 and Vitamin D either alone or in the combined treatment Overall design: EPC2 cells were seeded at high confluency and treated with either IL-13, or Vitamin D, or both for 6 hours. STAT6, VDR, H3K9ac, H3K27ac and H3K4me3 were assessed by ChIP-sequencing. Transcriptome was analyzed by RNA-sequencing