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Maternal UHRF1 is essential for early embryonic development and female fertilty.

NIAID Data Ecosystem2026-03-12 收录

胚胎发育表观遗传

母体-合子转换机制

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA659887 数据链接链接失效反馈

官方服务：

资源简介：

the research of maternal UHRF1 function in maternal-to-zygotic transition.

应用场景：

创建时间：

2020-08-28

胚胎发育表观遗传

细胞谱系分化

Early mouse development is regulated and accompanied by dynamic changes in chromatin modifications, including G9a-mediated histone H3 lysine 9 dimethylation (H3K9me2). Previously, we provided insights

NIAID Data Ecosystem50

CANTAC-seq analysis reveals the maternal factors E2f1 and Otx1 co-modulate minor zygotic gene transcription by a seesaw model (CANTAC-seq)

胚胎发育表观遗传

合子基因组激活

The transition from maternal to zygotic gene expression during zygotic genome activation (ZGA) is tightly associated with chromatin accessibility modulated by maternal transcription factors. However,

NIAID Data Ecosystem20

H2B-ubiq (NRO3).14-16 hr OR embryo

胚胎发育表观遗传

泛素化调控

H2B-ubiq (NRO3).14-16 hr OR embryo

ChEBI2011-10-12 更新00

Single-cell DNA replication profiling identifies spatiotemporal developmental dynamics of chromosome organization [HiC-seq]. Single-cell DNA replication profiling identifies spatiotemporal developmental dynamics of chromosome organization [HiC-seq]

染色体三维结构

胚胎发育表观遗传

In mammals, chromosomes are partitioned into megabase-sized topologically associating domains (TADs). TADs can be in either A (active) or B (inactive) subnuclear compartments, which correspond to earl

NIAID Data Ecosystem40

H3K9me3 abcam.14-16 hr OR embryo.Solexa

组蛋白修饰ChIP-seq

胚胎发育表观遗传

H3K9me3 abcam.14-16 hr OR embryo.Solexa

ChEBI2013-05-28 更新10