EPI-Clone dataset: Native hematopoiesis, old and young mouse

This is a dataset supporting the EPI-Clone manuscript: Targeted single cell methylation profiling of hematopoietic stem and progenitor cells (HSPCs) was performed with the scTAMseq method. Two experiments are included: HSPCs from a young mouse (12 weeks) and from a old mouse (100 weeks). Dataset is a seurat (v4) object with the following assays, reductions and metadata:  <br><b>ASSAYS</b>: DNAm: DNA methylation data, containing binary observations (0: amplicon not observed, i.e. dropout or absence of DNA methylation, 1: amplicon observed, i.e. DNA methylation). See the paper on scTAMseq <b>DIMENSIONALITY REDUCTION</b><b> </b>pca: PCA performed on the DNAm data umap: UMAP computed on the DNAm data <b>METADATA</b> Sample: The experiment that the cell is from, values are "Old" for the 100-wk mouse and “Young” for the 12-wk mouse CellType: Cell type annotation Pseudotime: Differentiation pseudotime PerformanceNonHhaI: Performance of the control amplicons in that cell TotalCounts: Number of reads on the Non-HhaI control amplicons