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Crystal structure of FGFR1 kinase domain in complex with compound 3

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Protein Data Bank Japan2023-11-22 更新2026-03-21 收录
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Crystal structure of FGFR1 kinase domain in complex with compound 3 Descriptor: 4-azanyl-3-(3,5-dimethyl-1-benzofuran-2-yl)-2-phenyl-6~{H}-pyrazolo[3,4-d]pyridazin-7-one, Fibroblast growth factor receptor 1 Authors: Xu, Y, Liu, Q. Deposit date: 2018-11-23 Release date: 2019-10-23 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.994 Å) Cite: Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design. J.Med.Chem., 62, 2019
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2018-11-23
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