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Complexes of PI3Kgamma with isoform selective inhibitors.

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Protein Data Bank Japan2024-05-01 更新2026-03-21 收录
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Complexes of PI3Kgamma with isoform selective inhibitors. Descriptor: 3-AMINO-6-{4-CHLORO-3-[(2,3-DIFLUOROPHENYL)SULFAMOYL]PHENYL}-N-METHYLPYRAZINE-2-CARBOXAMIDE, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM, SULFATE ION Authors: Foster, P.G, Lougheed, J.C. Deposit date: 2012-03-22 Release date: 2012-05-09 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.31 Å) Cite: The Discovery of a Novel Series of Potent and Orally Bioavailable Phosphoinositide 3-Kinase Gamma Inhibitors J.Med.Chem., 55, 2012

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2012-03-22
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