SpCas9 bound to 18-nucleotide complementary DNA substrate in the catalytic state
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SpCas9 bound to 18-nucleotide complementary DNA substrate in the catalytic state Descriptor: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, Non-target strand of 18-nucleotide complementary DNA substrate, ... Authors: Pacesa, M, Jinek, M. Deposit date: 2022-03-03 Release date: 2022-08-31 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (2.99 Å) Cite: R-loop formation and conformational activation mechanisms of Cas9. Nature, 609, 2022
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2022-03-03



