Functional and morphologic parameters in Protocol 1 (treatments started 60 days after renal ablation).

BW, body weight, g; Scr, serum creatinine, mg/dL; K+, serum potassium, mmol/L; %INT, fractional cortical interstitial area; MØ, density of tubulointerstitial macrophages, cells/mm2; AII+, density of tubulointerstitial cells staining positively for AII, cells/mm2; BG, blood glucose, mg/dL; Tg, triglycerides, mg/dL; S, Sham-operated; Nxpre, pretreatment Nx (60 days after renal ablation); Nx+V, untreated Nx; Nx+L, losartan-treated Nx; Nx+LH, Nx treated with losartan+hydrochlorothiazide; Nx+AHHz, Nx treated with amlodipine, hydrochlorothiazide, and hydralazine. Group Nx+V and all Nx treated groups studied 150 days after renal ablation. Results expressed as Mean ±1 SE;apbppre;cpdpep