Crystal Structure of the second bromodomain of human BRD3 in complex with the inhibitor JQ1

Protein Data Bank Japan2023-09-13 更新2026-03-21 收录

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Crystal Structure of the second bromodomain of human BRD3 in complex with the inhibitor JQ1 Descriptor: (6S)-6-(2-tert-butoxy-2-oxoethyl)-4-(4-chlorophenyl)-2,3,9-trimethyl-6,7-dihydrothieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-10-ium, 1,2-ETHANEDIOL, Bromodomain-containing protein 3 Authors: Filippakopoulos, P, Picaud, S, Qi, J, Keates, T, Felletar, I, Fedorov, O, Muniz, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Bradner, J.E, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2011-05-31 Release date: 2011-06-29 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.36 Å) Cite: Crystal Structure of the second bromodomain of human BRD3 in complex with the inhibitor JQ1 To be Published

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2011-05-31