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Crystal structure of the p110alpha catalytic subunit from homo sapiens in complex with activator 1938

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Protein Data Bank Japan2024-06-19 更新2026-05-24 收录
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Crystal structure of the p110alpha catalytic subunit from homo sapiens in complex with activator 1938 Descriptor: 1-[7-[[2-[[4-(4-ethylpiperazin-1-yl)phenyl]amino]pyridin-4-yl]amino]-2,3-dihydroindol-1-yl]ethanone, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Authors: Gong, G.Q, Bellini, D, Vanhaesebroeck, B, Williams, R.L. Deposit date: 2023-04-26 Release date: 2023-05-24 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (2.57 Å) Cite: A small-molecule PI3K alpha activator for cardioprotection and neuroregeneration. Nature, 618, 2023

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2023-04-26
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