Atox1

ENCODES a protein that exhibits ATPase binding; copper chaperone activity (ortholog); copper ion binding (ortholog); INVOLVED IN copper ion export; negative regulation of apoptotic process; response to oxidative stress; PARTICIPATES IN cisplatin drug pathway; ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); Chronic Hepatitis (ortholog); Colorectal Neoplasms (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-methylcholanthrene

编码一种具有ATPase结合位点的蛋白质；铜结合蛋白活性（同源）；铜离子结合（同源）；参与铜离子外排；负调控细胞凋亡过程；响应氧化应激；参与顺铂药物代谢途径；与肌萎缩侧索硬化症（同源）、慢性肝炎（同源）、结直肠癌（同源）相关；与17β-雌二醇、2,3,7,8-四氯二苯并-对氧杂蒽、3-甲基胆蒽相互作用。