Expression of GLI2 is repressed by GLI3R in the absence of Hh signaling
收藏reactome.org2025-03-24 收录
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Expression of the GLI2 gene is repressed in the absence of Hh signaling by GLI3R (Hu et al, 2006). GLI3R may exert its repression activity through the SKI-dependent recruitment of HDACs (Dai et al, 2002).
GLI2基因的表达在Hh信号通路缺失的情况下受到GLI3R(Hu等,2006年)的抑制。GLI3R可能通过依赖SKI的募集组蛋白去乙酰化酶(HDACs)(Dai等,2002年)来行使其抑制作用。
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