Molecular mechanisms of kidney injury in diabetic mice based on single-cell sequencing techniques

To investigate the pathogenic molecular mechanisms and signaling pathways of early diabetic kidney disease. We performed single-cell RNA sequencing on kidney tissue of early type 1 diabetic mice. The 4-week-old male C57BL/6J mice were randomly divided into two groups: normal group ( n=1 ) and type 1 diabetic group ( n=2 )