Phosphorylation of Wee1 kinase by Chk1
收藏reactome.org2025-03-22 收录
下载链接:
https://reactome.org/PathwayBrowser/#/R-HSA-75028
下载链接
链接失效反馈官方服务:
资源简介:
Phosphorylation of Wee1 by Chk1 stimulates Wee1 kinase activity.
Chk1对Wee1的磷酸化作用激发了Wee1激酶的活性。
应用场景:
提供机构:
Reactome相关数据集
Positive Regulation of Wee1 by Chk1 and 14-3-3 Proteins
Wee1 inactivates the Cdc2–cyclin B complex during interphase by phosphorylating Cdc2 on Tyr-15. The activity of Wee1 is highly regulated during the cell cycle. In frog egg extracts, it has been establ
PubMed Central00
ATR/CHK1/WEE1 dependency in SRSF2-mutated myeloid malignancies
The aim of this experiment is to characterize mRNA splicing in clones derived from the K562 cell line, which have been genetically engineered using CRISPR/Cas9 to carry SRSF2 mutations frequently obse
NIAID Data Ecosystem00
DataSheet_1_Combined inhibition of Wee1 and Chk1 as a therapeutic strategy in multiple myeloma.pdf
Multiple myeloma (MM) is a hematological malignancy characterized by an abnormal clonal proliferation of malignant plasma cells. Despite the introduction of novel agents that have significantly improv
NIAID Data Ecosystem00
ATR/CHK1/WEE1 dependency in SRSF2-mutated myeloid malignancies. ATR/CHK1/WEE1 dependency in SRSF2-mutated myeloid malignancies
The aim of this experiment is to characterize mRNA splicing in clones derived from the K562 cell line, which have been genetically engineered using CRISPR/Cas9 to carry SRSF2 mutations frequently obse
NIAID Data Ecosystem20
ATR/CHK1/WEE1 dependency in SRSF2-mutated myeloid malignancies
The aim of this experiment is to characterize mRNA splicing in clones derived from the K562 cell line, which have been genetically engineered using CRISPR/Cas9 to carry SRSF2 mutations frequently obse
NIAID Data Ecosystem00



