Spectrum of BIR-associated and spontaneous Lys+ mutations in MMR+ and msh2Δ strains.

aOther mutations include insertions and >1 bp deletions, as well as 1 bp deletions accompanied by base substitutions;*Percentage of 1 bp deletions occurring in the poly-A run is statistically significantly different from the isogenic wild type strain using Fisher's Exact Test (pFigure 1D and Table S1; DSB, double-strand break; WT, wild type.