Cancer-associated chromosomal rearrangements can result in the expression of numerous pathogenic fusion proteins. The mechanisms via which the fusion proteins contribute to oncogenesis are largely unk
本数据集为《Comparative profiling of skeletal muscle models reveals heterogeneity of transcriptome and metabolism》论文的补充数据,包含2个Excel文件。数据基于GEO数据库的肌管和骨骼肌组织公开数据,经RMA归一化、同源基因匹配及基因符号聚合处理,用于揭示不同骨骼肌模型的转录组与代谢异质性。 论
Poly (ADP-ribose) polymerase 1 (PARP-1) is a critical enzyme involved in DNA damage repair and recombination, and shows great potential for drug development in the treatment of cancers with defective
In this study, α-aminophosphonates and oxazaphosphinanes were synthesized and evaluated for their potential anticancer activity. The objective was to assess their cytotoxic effects against various can