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PARPi-resistant SUM149PT BRCA1 amplicon sequencing

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NIAID Data Ecosystem2026-03-12 收录
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SUM149PT harbours a homozygous 1-bp frameshift deletion in BRCA1. We performed deep amplicon DNA sequencing on this locus in parental and talazoparib- resistant clones, as well as a non-malignant BRCA1 wildtype cell line, MCF10A.

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2020-11-27
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