The systemic metabolic shifts that occur during aging and the local metabolic alterations of a tumor, its stroma and their communication cooperate to establish a unique tumor microenvironment (TME) th
Transcriptional profiling showed that adaptation to nutrient and oxygen deprivation condition is associated with widespread transcriptional reprogramming resulting in the induction of glycolysis and a
Metabolomics datasets as follows: Metabolomics MDA CAF-CDM vs plastic: Non-targeted metabolomics analysis of metabolistes extracted from breast cancer cells (MDA-MB-231), grown on plastic or cancer as
Carcinoma-associated fibroblasts (CAFs) consist of heterogeneous subpopulations and play a critical role in the dynamics of the tumor microenvironment. Previously, the extracellular signals of CAFs ha
