Functional and structural differences in adults with dyslexia

# README

This dataset was collected with the aim to investigate functional and structural differences in adults with dyslexia.

The data was collected at the University Hospital of Ghent, Belgium on a 3T Siemens Prisma scanner from November 2021 - May 2022.

Ethics approval was obtained from the medical ethical committee of Ghent University Hospital (approval number BC-09822).

The dataset consists of

- T1-weighted image

- Diffusion weighted images:
dwi series with A-P phase encoding (b-shells: 0,1200,3000)
a b-zero weighted scan with P-A phase encoding for EPI distortion correction

- Task related functional MRI images (all block designs):
covert letter fluency task
visual rhyme decision task
lexical decision task
fieldmap for EPI distortion correction

## Participants

Thirty-five adults with a diagnosis of dyslexia and 35 individuals without any diagnosis of language or reading impairment were recruited for this study.

Inclusion criteria were:
- Dutch as a first language
- age between 18 and 40
- right-handedness

All participants had normal or corrected-to-normal vision and reported no history of brain injury or neurological disease. All participants in the dyslexia group received a diagnosis of dyslexia from a trained professional, either while they were at school or in the context of receiving disability services at university/college.

## Further materials

The task scripts and stimuli for the fMRI data are available to download from OSF at https://osf.io/d8e9b/

# 数据集说明
本数据集的采集旨在探究阅读障碍成年人的功能与结构差异。
该数据于2021年11月至2022年5月期间，在比利时根特大学附属医院的3T西门子Prisma扫描仪上完成采集。
本研究已获得根特大学附属医院医学伦理委员会批准，批准号为BC-09822。

本数据集包含以下内容：
- T1加权成像（T1-weighted image）
- 弥散加权成像：
采用前后位（A-P）相位编码的弥散加权序列（b值：0、1200、3000）
用于EPI（Echo Planar Imaging）畸变校正的后前位（P-A）相位编码b=0加权扫描
- 任务态功能磁共振成像（均采用组块设计）：
隐蔽性字母流畅性任务
视觉韵脚判断任务
词汇判断任务
用于EPI（Echo Planar Imaging）畸变校正的场图（fieldmap）

## 受试者
本研究共招募35名确诊阅读障碍的成年人，以及35名无任何语言或阅读障碍诊断的健康个体。
纳入标准如下：
- 荷兰语为母语
- 年龄介于18至40周岁之间
- 右利手
所有受试者视力正常或经矫正后可达正常水平，无脑损伤或神经系统疾病史。阅读障碍组的所有受试者均由专业人员确诊，确诊时机可为其在校就读期间或在大学/学院接受残疾服务期间。

## 补充材料
本研究功能磁共振成像数据对应的任务脚本与刺激材料，可从开放科学框架（Open Science Framework，OSF）平台的https://osf.io/d8e9b/ 链接下载获取。

搜集汇总

背景与挑战

背景概述

该数据集包含70名成人（35名阅读障碍患者和35名正常对照）的MRI数据，旨在研究阅读障碍的功能和结构差异。数据采集于3T Siemens Prisma扫描仪，包括结构MRI、扩散加权成像和任务相关功能MRI，涵盖了字母流畅性、视觉押韵判断和词汇决策等多种任务。