Transcriptional profiling of medium spiny neurons in the striatum of Drd2-TRAP (CP101) mice administered either saline or cocaine

TRAP translational profiling is a method that allows investigators to genetically characterize specific cell types in complex tissues such as mouse brain. Using this technique we obtained RNA-Seq data from actively translating transcripts present in medium spiny neurons in the whole striatum of adult Drd2-EGFP/Rpl10a (CP101) mice that were administered either saline or cocaine. Overall design: Short access cocaine intravenous self-administration study; TRAP-Seq of medium spiny neurons in the whole striatum of adult Drd2-EGFP/Rpl10a (CP101) mice administered either saline or cocaine