Proliferation and Tumorigenesis of a Murine Sarcoma Cell Line in the Absence of Dicer

ChEBI2012-08-20 更新2026-07-21 收录

肿瘤发生机制

基因功能缺失

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-34825 数据链接链接失效反馈

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资源简介：

Proliferation and Tumorigenesis of a Murine Sarcoma Cell Line in the Absence of Dicer

创建时间：

2012-08-20

NGS-mRNA in lung tissues in RAG1-/- and in RAG1-/- Sgo1-/+ mice

基因表达分析

肿瘤发生机制

We compared lung mRNA expression profiles between RAG1-/- control and RAG1-/- Sgo1-/+ chromosome instability model mice. RAG1-/-Sgo1-/+ mice developed significantly more spontaneous lung tumors. Char

NIAID Data Ecosystem80

Splicing Variation Contributes to Functional Dysregulation of Genes in Acute Myeloid Leukemia

AML可变剪接

基因功能缺失

Acute Myeloid Leukemia (AML) has been associated with somatic mutations in numerous genes; however, the penetrance of these mutations is low. Here we investigate the contribution of alternative splici

NIAID Data Ecosystem60

Wnt-Induced Stabilization of KDM4C Is Required for Wnt/beta-Catenin Target Gene Expression and Tumorigenesis

Wnt信号通路表观遗传

肿瘤发生机制

Wnt/beta-catenin signaling is essential for stem cell regulation and cancer formation by activation of target genes transcription. For transcriptional activation, the histone around promoters needs to

NIAID Data Ecosystem40

Transcription profiling of HSCs from SYCNRIP WT and KO mice. Transcription profiling of HSCs from SYCNRIP WT and KO mice

干细胞转录组学

基因功能缺失

SYNCRIP depletion results in HSCs losing their self renewal abilities. Next generation sequencing was conducted in SYNCRIP WT and KO HSCs to investigate the transcriptional changes that occur, and res

NIAID Data Ecosystem60

Identification of a novel TINCR-EGFR signaling pathway loop which initiates receptor tyrosine kinases cascade and confers tumorigenesis in human cancer

癌症信号通路

肿瘤发生机制

RNA sequencing was performed to investigate the potential crosstalk between TINCR and microRNAs. Overall design: microRNA profiles of T47D with TINCR knockdown and scramble were generated by deep sequ

NIAID Data Ecosystem50

Proliferation and Tumorigenesis of a Murine Sarcoma Cell Line in the Absence of Dicer

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