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Crystal structure of the human CDK12-cyclin K complex bound to AMPPNP

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Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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Crystal structure of the human CDK12-cyclin K complex bound to AMPPNP Descriptor: CYCLIN-DEPENDENT KINASE 12, CYCLIN-K, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER Authors: Dixon Clarke, S.E, Elkins, J.M, Pike, A.C.W, Nowak, R, Goubin, S, Mahajan, R.P, Kopec, J, Froese, S, Tallant, C, Carpenter, E.P, Mackenzie, A, Faust, B, Burgess-Brown, N, von Delft, F, Arrowsmith, C, Edwards, A.M, Bountra, C, Bullock, A. Deposit date: 2014-04-04 Release date: 2014-05-21 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Structures of the Cdk12/Cyck Complex with AMP-Pnp Reveal a Flexible C-Terminal Kinase Extension Important for ATP Binding. Sci.Rep., 5, 2015

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2014-04-04
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