Activation of RXRa reprograms chromatin accessibility to protect against acute kidney injury [ChIP-seq]

Purpose: To explore whether the differences in chromatin occupancy of RXRa correlate with distinct gene expression in PTCs of MI and SI Methods: Proximal tubules were isolated for RXRa ChIP-seq Results: Using an optimized data analysis workflow, we mapped reads to the mouse genome (mm10). Conclusions: We mapped the chromatin occupancy of RXRa. Overall design: ChIP sequencing with RXRa antibodies for proximal tubular cells isolated in injury kidneys