Result of differential analysis of enriched regions identified in MTy and Ty samples.

The columns show the differential region found and its closest gene. The information about the Peak is respectively the ID used internally (Internal ID), location of the peak (Chromosome name, start and end coordinates), width of the peak extension, attributes calculated by DiffBind (Concentration, Ty and MTy samples Concentration, Fold, p.value, FDR). DiffBind conc column show the mean read concentration over all the samples (the default calculation uses log2 normalized ChIP read counts with control read counts subtracted) and the mean concentration over the first (Ty) group and second (MTy) group. The Fold column shows the difference in mean concentrations between the two groups (Conc_Ty–Conc_MTy), with a positive value indicating increased binding affinity in the Ty group and a negative value indicating increased binding affinity in the MTy group. The final two columns give confidence measures for identifying these sites as differentially bound, with a raw p-value and a multiple testing corrected FDR in the final column. The information about the feature is its location (chrm, start, end, strand) in genome, disposal of the peak in relation of the feature, distance of peak from start of the feature, shortest distance of peak from feature, feature identification in TriTrypDB database and feature name. Each Excel sheet is concern to Narrow or Broad regions. (XLSX)