Cancer Outcome Associated (COA) genes in the baseline signature are defined by their significant association with breast cancer disease-free survival.

*Cancer Outcome Assocaited (COA) genes were identified as follows. For each gene in the unbiased signature, a t-test was applied comparing average expression in the above median patient group vs the below median patient group. Patients were assigned to each group based on median expression of all baseline genes (94 genes). All genes with p<0.01 that were expressed at higher or lower (genes in italic) levels in the above median patient group are listed here (n = 55 genes).