rDNA Array Length is a Major Determinant of Replicative Lifespan in Budding Yeast.
收藏NIAID Data Ecosystem2026-03-13 收录
官方服务:
资源简介:
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
应用场景:
创建时间:
2022-07-05
相关数据集
Identification of novel genetic factors that control chronological lifespan in Schizosaccharomyces pombe during long term nitrogen starvation in a competitive environment
In this study we identified novel genetic players of chronological lifespan (CLS) by studying survival of quiescent fission yeast in a nitrogen depleted environment where cells are in a non-dividing s
NIAID Data Ecosystem70
Effects of Mutations in DNA Repair Genes on Formation of Ribosomal DNA Circles and Life Span in Saccharomyces cerevisiae
A cause of aging in Saccharomyces cerevisiae is the accumulation of extrachromosomal ribosomal DNA circles (ERCs). Introduction of an ERC into young mother cells shortens life span and accelerates the
PubMed Central50
Loss of major nutrient sensing and signaling pathways suppresses starvation lethality in electron transport chain mutants (DenseTimeCourse). Loss of major nutrient sensing and signaling pathways suppresses starvation lethality in electron transport chain mutants (DenseTimeCourse)
Here we sought to comprehensively characterize the role of the electron transport chain in yeast models of aging. Using a panel of ETC mutants, we observed that ETC mutants fail to survive starvation
NIAID Data Ecosystem30
Analysing the impact of extrachromosomal rDNA circles (ERCs) on the ageing yeast transcriptome [genome]. Analysing the impact of extrachromosomal rDNA circles (ERCs) on the ageing yeast transcriptome [genome]
Here we analysed the widespread disruption of gene expression that accompanies yeast ageing, and surprisingly observed that this is completely independent of ERCs. Furthermore, we could not find subse
NIAID Data Ecosystem60
The role of Sgf73 occupancy
Sgf73, a core component of the SAGA (Spt-Ada-Gcn5 Acetyltransferase) co-activator complex, is the yeast orthologue of ataxin-7, which in humans undergoes CAG ? polyglutamine repeat expansion to produc
NIAID Data Ecosystem40



