Co-crystal structure of MDM2 with Inhibitor Compound 4
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Co-crystal structure of MDM2 with Inhibitor Compound 4 Descriptor: E3 ubiquitin-protein ligase Mdm2, [(2R,5R,6R)-4-[(1S)-2-(tert-butylsulfonyl)-1-cyclopropylethyl]-6-(3-chlorophenyl)-5-(4-chlorophenyl)-3-oxomorpholin-2-yl]acetic acid Authors: Shaffer, P.L, Huang, X, Yakowec, P, Long, A.M. Deposit date: 2014-01-07 Release date: 2014-03-19 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.602 Å) Cite: Selective and Potent Morpholinone Inhibitors of the MDM2-p53 Protein-Protein Interaction. J.Med.Chem., 57, 2014
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2014-01-07
