Plexiform neurofibromas (PN) are benign nerve sheath Schwann cell tumors, common in patients with neurofibromatosis type 1 (NF1), that are characterized by biallelic mutations in the NF1 tumor suppres
Analysis of the genetic changes in human tumors is often problematical because of the presence of normal stroma and the limited availability of pure tumor DNA. However, large amounts of highly reprodu
CSR, Complete surgical removal; Ct, Chemotherapy; NA, Not available.***>5 years free of disease;***DNA analysis estimated from their parents.The number of cancer cases in each family was shown in the
Background: Pheochromocytoma and paraganglioma (PPGL) are rare neuroendocrine tumors arising from chromaffin cells in the adrenal medulla and extra-adrenal ganglia, respectively. The study was aimed t
A comparison of RNA expression profiles from leukemic cells of 8 single B-ALL patients at diagnosis and relapse. For all patients, clonality of the blast cells at diagnosis and relapse was demonstrate
