Effects of SF3B1 mutation on blast cells from patients with MDS
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE133128
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Effects of SF3B1 mutation on blast cells from patients with MDS Here we isolated bone marrow blast cells from 7 patients with myelodysplastic syndrome (MDS): 4 patients with the SF3B1 -K700E mutation and 3 patients without SF3B1, U2AF1, or SRSF2 mutations (WT). RNA was prepared and RNAseq performed to determine the effects of SF3B1-K700E on gene expression and pre-mRNA splicing. WT (n=3), K700E (n=4)
创建时间：
2020-03-20
