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Microglia-derived Il6 deficient Vs floxed mice with/without cryolesion

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NIAID Data Ecosystem2026-03-12 收录
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We have examined the role of microglia-derived IL-6 by analyzing the transcriptome of the brain cortex following a cryolesion. We performed oligonucleotide array analysis using the right fronto-parietal cortex of microglia-derived Il6 deficient (Il6ΔMic) and floxed (Il6lox/lox) mice , under control and cryolesion conditions. Four-condition experiment: control floxed mice; cryolesioned floxed mice; control microglia-derived Il6 deficient mice; cryolesioned microglia-derived Il6 deficient mice Biological replicates: 4 per condition.

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2021-01-04
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