Stereoselective α‑Hydroxylation of Amides Using Oppolzer’s Sultam as Chiral Auxiliary
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An Oppolzer’s sultam-based highly stereoselective α-hydroxylation of amides was developed to deliver the desired products in good yield and excellent diastereoselectivity (>20/1). The generally crystalline products and the recyclability of the chiral auxiliary illustrate the practicability and scalability of the current approach.
创建时间:
2016-05-02



