Lymphatic endothelial cell identity is controlled by a GATA2 bound enhancer (RNA-Seq)
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https://www.ncbi.nlm.nih.gov/sra/SRP336852
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资源简介:
This study investigates the impact on the transcriptome of lymphatic endotheial cells of a 5bp deletion (GATA2 binding site) in an enhancer element 11kb upstream of the Prox1 gene. Overall design: Comparison of RNA from deletion mutant and wildtype lymphatic endothelial cells isolated directly from embryos at E14.5. Also, to assess haematopoietic potential, comparison of the same samples after 7d co-culture on OP9 feeder cells.
创建时间:
2023-02-11



