Predictors of Quality of Life in Healing of Venous Leg Ulcers: A Quasi-Experimental Study in a Brazilian Wound Care Center

Objectives: To compare the evolution of Quality of Life (QoL) between individuals whose Venous Leg Ulcers (VLUs) healed and those whose ulcers did not heal after one year of treatment in a specialized chronic wound care center, and to identify the most impacted aspects of QoL following treatment. Method: This was a longitudinal, observational, quasi-experimental, and non-randomized study involving patients with VLUs. A convenience sample of individuals receiving care was followed for at least one year and treated with either compression therapy or conventional care. QoL was measured using the Medical Outcomes Short-Form Health Survey (SF-36) and the Charing Cross Venous Ulcer Questionnaire (CCVUQ). Study participants were categorized into a Healed Group (HG) and a Non-Healed Group (NHG). Results: A total of 103 individuals completed the study, of whom 43 (43.7%) achieved ulcer healing after one year of treatment. Binary logistic regression analysis revealed that VLU healing was a significant predictor of improved outcomes, particularly in the SF-36 domains of Physical Role Functioning (R²=0.53, p