α7 nicotinic acetylcholine receptor signaling modulates the inflammatory phenotype of fetal brain microglia: first evidence of interference by iron homeostasis.. Ovis aries

We sequenced mRNA from 7 microglia extracted from sheep fetuses exposed to LPS, agonist and antagonist of α7 nicotinic acetylcholine receptor to determine signaling pathway through modeling of α7 during inflammation. Overall design: Examination of genetic expression in microglia after α7 nicotinic acetylcholine receptor modeling with agonistic and antagonistic drug.