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A locus at 6p21.33 shows differential expression in peripheral mononuclear cells

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NIAID Data Ecosystem2026-03-10 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE77865
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Analysis of PBMC gene expression levels according to homozygous haplotype rs9380217- rs4947296. The hypothesis tested in the present study was that the haplotype rs9380217- rs4947296 at locus 6p21.33 influence gene expression of the immune response. Results provide important information involving class II HLA genes and TWEAK/Fn14 pathway Total RNA obtained from three peripheral mononuclear cells homozygous haplotype rs9380217/rs4947296 (CC/TT_1; CC/TT_2; CC/TT_3) compared to three homozygous haplotype rs9380217/rs4947296 (TT/CC_1; TT/CC_2; TT/CC_3).
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2018-08-13
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