Additional file 2: Table S2. of Whole-genome transcription and DNA methylation analysis of peripheral blood mononuclear cells identified aberrant gene regulation pathways in systemic lupus erythematosus

Downregulated genes in PBMC of SLE patients compared with normal controls by microarray analysis. S2-1 showed the complete list of 550 downregulated genes in SLE. Three group comparisons, SLE (LN− and LN+) vs. NC (S2-2), SLE LN− vs. NC (S2-3), and SLE LN+ vs. NC (S2-4), were performed to identify downregulated genes by fold change (FC) > 1.2 and p < 0.05 within each group. The 550 common downregulated genes in SLE were then selected from the genes identified in each of the three group comparisons. S2-5 showed gene expression of 550 common downregulated genes represented by normalized intensity in SLE. (XLSX 710 kb)