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Additional file 2: Table S2. of Whole-genome transcription and DNA methylation analysis of peripheral blood mononuclear cells identified aberrant gene regulation pathways in systemic lupus erythematosus

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Downregulated genes in PBMC of SLE patients compared with normal controls by microarray analysis. S2-1 showed the complete list of 550 downregulated genes in SLE. Three group comparisons, SLE (LN− and LN+) vs. NC (S2-2), SLE LN− vs. NC (S2-3), and SLE LN+ vs. NC (S2-4), were performed to identify downregulated genes by fold change (FC) > 1.2 and p < 0.05 within each group. The 550 common downregulated genes in SLE were then selected from the genes identified in each of the three group comparisons. S2-5 showed gene expression of 550 common downregulated genes represented by normalized intensity in SLE. (XLSX 710 kb)

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2016-12-14
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