Crystal structure of TYK2 kinase with compound 19
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Crystal structure of TYK2 kinase with compound 19 Descriptor: (1S)-2,2-difluoro-N-[(1S,5R,6R)-3-{5-fluoro-2-[(1-methyl-1H-pyrazol-4-yl)amino]pyrimidin-4-yl}-6-methyl-3-azabicyclo[3.1.0]hexan-1-yl]cyclopropane-1-carboxamide, Non-receptor tyrosine-protein kinase TYK2 Authors: Vajdos, F.F. Deposit date: 2020-01-29 Release date: 2020-04-08 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.18 Å) Cite: Design and optimization of a series of 4-(3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-2-amines: Dual inhibitors of TYK2 and JAK1. Bioorg.Med.Chem., 28, 2020
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2020-01-29
