Ryr2

ENCODES a protein that exhibits calcium-induced calcium release activity; ryanodine-sensitive calcium-release channel activity; scaffold protein binding; INVOLVED IN calcium ion transmembrane transport; manganese ion transmembrane transport; monoatomic ion transmembrane transport; PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH congestive heart failure; Experimental Diabetes Mellitus; pulmonary hypertension; FOUND IN A band; extrinsic component of cytoplasmic side of plasma membrane; nuclear envelope; INTERACTS WITH (S)-nicotine; 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine; 17beta-estradiol

编码一种表现出钙诱导钙释放活性、ryanodine敏感的钙释放通道活性、支架蛋白结合功能的蛋白质；参与钙离子跨膜转运、锰离子跨膜转运以及单原子离子跨膜转运；参与阿替洛尔药代动力学途径、肾上腺素能β受体激动剂及β-阻滞剂药代动力学途径、胺碘酮药代动力学途径；与充血性心力衰竭、实验性糖尿病、肺高血压相关；存在于某一带区；为质膜胞质侧的外在成分、核被膜所包含；与(S)-尼古丁、1-[(2,3,4-三甲氧基苯基)甲基]哌嗪、17β-雌二醇相互作用。