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Reductive CO<sub>2</sub> Fixation via Tandem C–C and C–N Bond Formation: Synthesis of Spiro-indolepyrrolidines

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NIAID Data Ecosystem2026-03-10 收录
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We describe herein a tandem C–C and C–N bond-forming reaction in the reductive functionalization of CO2, an abundant and cheap C1 chemical feedstock. This catalytic metal-free CO2 fixation afforded spiro-indolepyrrolidines by dearomatization of tryptamine derivatives with broad scope and good functional group tolerance under mild conditions.

创建时间:
2017-08-04
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