首页/数据集/Additional file 2 of Bisecting GlcNAc enhances CD8+ T cell-mediated killing of breast cancer by suppressing PD-L1 expression and its binding to PD-1

Additional file 2 of Bisecting GlcNAc enhances CD8+ T cell-mediated killing of breast cancer by suppressing PD-L1 expression and its binding to PD-1

Figshare2025-08-04 更新2026-04-28 收录

肿瘤免疫疗法

免疫检查点调控

数据链接：

https://figshare.com/articles/dataset/Additional_file_2_of_Bisecting_GlcNAc_enhances_CD8_T_cell-mediated_killing_of_breast_cancer_by_suppressing_PD-L1_expression_and_its_binding_to_PD-1/29826223 数据链接链接失效反馈

官方服务：

资源简介：

Supplementary Material 2

应用场景：

创建时间：

2025-08-04

相关数据集

表达IFNα的间充质基质细胞赋予T细胞强大的抗肿瘤免疫力

肿瘤免疫疗法

细胞治疗

免疫检查点阻断疗法的出现已经彻底改变了癌症治疗方法。然而，只有少数不同类型的肿瘤患者从这些治疗中获益。针对肿瘤组织微环境中免疫情况的新策略具有巨大的前景。在此，我们创造了过表达IFNα的间充质基质细胞（IFNα-MSCs）。在直接注射到肿瘤中后，我们发现这些细胞可以有效地消除多种类型的肿瘤。有趣的是，IFNα-MSCs的肿瘤内注射也可以在远处的肿瘤中产生特异性的抗肿瘤作用。这些IFNα-MSCs促

干细胞与再生医学数据中心2023-05-03 更新130

CD47 regulates the immunodynamics of CD8+ T cells. CD47 regulates the immunodynamics of CD8+ T cells

免疫检查点调控

细胞免疫动力学

CD47 is a transmembrane glycoprotein that is ubiquitously expressed in different organs and tissues (Barclay and Van den Berg 2014; Liu, et al. 2017). In the human immune system, CD47 interacts with s

NIAID Data Ecosystem80

Papalexi, E., Mimitou, E.P., Butler, A.W. et al. ECCITE

单细胞多组学

免疫检查点调控

ECCITE seq data set from the paper "Characterising the molecular regulation of inhibitory immune checkpoints with multi-modal single-cell screens" and the R tutorial demonstrating the Mixscape package

NIAID Data Ecosystem40

eccite.h5mu

单细胞多组学

免疫检查点调控

Figshare2022-01-24 更新80

scRNAseq of CD45+ cells within PDAC tumors treateted with CD40/ICB. scRNAseq of CD45+ cells within PDAC tumors treateted with CD40/ICB

肿瘤免疫疗法

转录组分析

Goal: determine how transcriptome of immune cells within the tumor microenvironment changes as a function of CD40 agonist and/or immune checkpoint blockade (anti-PD-1 AND anti-CTLA-4; "ICB") therapy O

NIAID Data Ecosystem40