Crystal structure of IgG1-Fc-MST-HN (efgartigimod)
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Crystal structure of IgG1-Fc-MST-HN (efgartigimod) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Pannecoucke, E, Savvides, S.N. Deposit date: 2021-10-28 Release date: 2022-09-28 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The Fab region of IgG impairs the internalization pathway of FcRn upon Fc engagement. Nat Commun, 13, 2022
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2021-10-28
