Transcriptomic profiling reveals distinct molecular signatures among lesion types in hidradenitis suppurativa

This study investigated the transcriptome of the various hidradenitis suppurativa lesion types using bulk RNA sequencing. Overall design: Three-millimetre punch biopsies were collected from draining tunnels (purulent discharge at rest or to palpation) and non-draining tunnels (no purulent discharge) from 20 hidradenitis suppurativa patients and normal skin from eight healthy donors.